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pentobarbital will minimize the extent or result of fosamprenavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

pentobarbital will decrease the extent or influence of abemaciclib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of abemaciclib with strong CYP3A4 inducers reduces plasma concentration of abemaciclib and its metabolites.

pentobarbital will decrease the level or effect of almotriptan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

pentobarbital will lessen the extent or effect of capivasertib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Potent or average CYP3A inducers lessen capivasertib publicity, which may reduce efficacy.

pentobarbital will minimize the extent or influence of brexpiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Double brexpiprazole dose over one-2 months if administered with a solid CYP3A4 inducer.

pentobarbital will lessen the extent or impact of bosentan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.

pentobarbital will reduce the extent or read more result of elagolix by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

lasmiditan, pentobarbital. Either will increase effects of one other by sedation. Use Caution/Keep an eye on. Coadministration of lasmiditan and also other CNS depressant drugs, such as Alcoholic beverages haven't been evaluated in clinical experiments. Lasmiditan could induce sedation, in addition to other cognitive and/or neuropsychiatric adverse reactions.

pentobarbital will decrease the extent or effect of efavirenz by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unidentified.

Comment: Barbiturates might improve adverse effects, which includes respiratory melancholy, produced by toxic doses of TCAs. With therapeutic doses of TCAs, barbiturates improve metabolism and decrease blood concentrations of TCAs.

fentanyl transdermal and pentobarbital both equally increase sedation. Stay away from or Use Alternate Drug. Restrict use to patients for whom substitute treatment method options are inadequate

pentobarbital will minimize the level or outcome of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

pentobarbital will reduce the extent or effect of nimodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unidentified.

pentobarbital will lower the level or outcome of eltrombopag by influencing hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep track of.